Na klepvervanging dient nog gedurende 6 weken post-operatief behandeld te worden met antibiotica.

Antibioticakeuze passend bij gevonden verwekker.

SWAB guidelines for the antimicrobial treatment of infective endocarditis (June 2019): Treatment of prosthetic valve endocarditis differs in many, but not all cases from native valve endocarditis. Treatment for prosthetic valve endocarditis may be longer and consist of multiple antimicrobial agents. The committee likes to emphasize that bioprosthetic valves contain metal susceptible to biofilm formation just like mechanical prosthetic valves. Hence, where the document says "prosthetic valves", it refers to bio-valves and mechanical valves.